North-East India Helminth Parasite Information Database

Objectives of the Project

  • To establish an integrated web-based approach database and research interface related to parasitology research.
  • Characterization of parasite biodiversity in mammalian livestock (cattle, sheep, goat, pig etc.) and other food animals in NER of India by integration of comparative genomics and molecular systematics: for identification and classification of parasites to define geographic distribution, genetic variability, if any among the different geographical isolates and host associations and to recognize the impact of cryptic, emergent, exotic and invasive pathogens.
  • Identification of species-specific molecular markers for accurate diagnosis.
  • Polymorphic surveys that address the population biology and movements of the parasites, informing epidemiological studies.
  • Comparative insilico study of food-borne trematode and other helminthic infections (namely, Trematode: Paragonimus (lung fluke), Fasciola and other liver flukes, Fasciolopsis and other gastro-intestinal flukes; Cestode: Taenia & its bladderworm; Nematode: Ascaris, hookworm, filarial worm), which are zoonotic in nature (i.e. transferable between animals and man) under broader areas like
  • Application of sequence based and structure based approach for identification and assignment of disease genes, use of SNPs for identification of genetic traits etc.
  • Proteome analysis with a focus on revelation of gene families and duplicated genes and identification of ancient conserved domains.
  • Synteny and gene order comparison across pathogenic parasites.
  • Metabolic pathway and phylogeny reconstruction.